| Rank | Total | School | Years |
| 1 | 23 | Pembroke Hill | 1962, 1963, 1965, 1967, 1975, 1978, 1979, 1980, 1989, 1990 (2), 1991 (2), 1992, 1998, 2000, 2002, 2005, 2009, 2010, 2012, 2019, 2024 |
| 2 | 20 | Rockhurst | 1976, 1983, 1996, 1997, 1998, 1999, 2000, 2001 (2), 2002, 2003, 2004 (2), 2005, 2007, 2013, 2014 (2), 2016, 2024 |
| 3 | 17 | MICDS | 1993, 1994, 1995, 1996, 1997, 1998, 1999, 2001, 2007, 2008, 2009, 2011, 2015, 2016 (2), 2018, 2021 |
| 4 | 15 | Clayton | 1966, 1985, 1986, 1987, 1988, 1995, 2004, 2005, 2006 (2), 2011, 2012, 2013, 2023, 2024 |
| 5 | 12 | John Burroughs | 1956, 1957, 1999, 2000, 2001, 2002, 2003, 2004, 2014, 2019, 2021, 2023 |
| 6 | 11 | Ladue Horton Watkins | 1960, 1962, 1978, 1985 (2), 1988 (2), 2003, 2023 (2), 2024 |
| 7 | 10 | Westport | 1928, 1931 (2), 1932, 1935, 1937, 1940, 1942, 1943, 1948 |
| 8 | 9 | SLUH | 1952, 1963, 1970, 1980, 1981, 1994, 1995, 2007, 2022 |
| 8 | 9 | Rock Bridge | 2008, 2009, 2010, 2011, 2012 (2), 2018, 2019, 2022 |
| 10 | 8 | Central (St. Joseph) | 1951, 1974, 1992, 1993 (2), 1994, 1995, 2003 |
| 11 | 7 | Priory | 1986, 2017, 2021 (2), 2022, 2023, 2024 |
| 12 | 6 | Beaumont | 1937, 1938 (2), 1939, 1941, 1953 |
| 12 | 6 | Webster Groves | 1941, 1942, 1943, 1957, 1958, 1959 |
| 14 | 5 | Chaminade College Prep | 1990, 1991 (2), 1992, 2006 |
| 14 | 5 | Glendale | 1982, 1989, 1996, 2010, 2011 |
| 14 | 5 | Barstow | 2015, 2017, 2018, 2021, 2022 |
| 17 | 4 | Roosevelt | 1950, 1964, 1965, 1966 |
| 17 | 4 | University City | 1933, 1934, 1935, 1969 |
| 17 | 4 | Lindbergh | 1980, 1981, 1983, 1984 |
| 17 | 4 | Principia | 1972, 1980, 1984, 1985 |
| 17 | 4 | Kirkwood | 1951, 1998, 2000, 2006 |
| 17 | 4 | Parkway South | 2015, 2016, 2017, 2018 |
| 17 | 4 | Christian Brothers College | 1997, 2009, 2017, 2019 |
| 24 | 3 | Southwest High School (Kansas City) | 1926, 1927, 1928 |
| 24 | 3 | Central High School (STL) | 1949, 1953, 1954 |
| 24 | 3 | Sumner | 1974, 1975, 1976 |
| 24 | 3 | Oak Park | 1984, 1986, 1987 |
| 24 | 3 | Pattonville | 1967, 1973, 2005 |
| 24 | 3 | Thomas Jefferson Independent Day | 2007, 2008, 2010 |
| 24 | 3 | Parkway West | 1989, 1999, 2015 |
| 24 | 3 | Westminster Christian Academy | 2013, 2014, 2021 |
| 32 | 2 | Central (Springfield) | 1936 (2) |
| 32 | 2 | Paseo Academy | 1932, 1961 |
| 32 | 2 | McCluer | 1968, 1969 |
| 32 | 2 | Lutheran North | 1968, 1971 |
| 32 | 2 | Country Day (St. Louis) | 1934, 1977 |
| 32 | 2 | Hazelwood Central | 1977, 1979 |
| 32 | 2 | Parkview | 1973, 1986 |
| 32 | 2 | De Smet Jesuit | 1982, 1987 |
| 32 | 2 | Benton | 1987, 1988 |
| 32 | 2 | Jefferson City | 1949, 1990 |
| 32 | 2 | Joplin | 2008, 2013 |
| 32 | 2 | Warrensburg | 1992, 2022 |
| 32 | 2 | Whitfield | 2022, 2023 |
| 45 | 1 | Rich Hill | 1929 |
| 45 | 1 | Central (Kansas City) | 1930 |
| 45 | 1 | McBride High School | 1940 |
| 45 | 1 | Blewett High School | 1947 |
| 45 | 1 | Southeast | 1952 |
| 45 | 1 | Parkway Central | 1961 |
| 45 | 1 | South Pemiscot | 1982 |
| 45 | 1 | Springfield Catholic | 1989 |
| 45 | 1 | St. Pius X (Festus) | 1993 |
| 45 | 1 | School of the Ozarks | 1994 |
| 45 | 1 | Liberty | 2002 |
| 45 | 1 | Savannah | 2024 |