Class 1 State Semifinal 1 Cape Girardeau, MO |
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| New Haven (26-7-3) Class 1 District 12 | |
| Valle Catholic (30-3) Class 1 District 4 | |
| TBD |
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| Winona (19-9-2) Class 1 District 5 | |
| Northland Christian (32-3-3) Class 1 District 15 | |
| TBD |
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| Strafford (31-4-1) Class 2 District 12 | |
| St. Pius X (Festus) (24-8) Class 2 District 3 | |
| TBD |
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| Hermann (29-6-1) Class 2 District 7 | |
| St. Michael the Archangel (18-14-2) Class 2 District 14 | |
| TBD |
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| Helias Catholic (31-4-1) Class 3 District 10 | |
| Lutheran South (30-4-2) Class 3 District 3 | |
| TBD |
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| Ozark (30-7-2) Class 4 District 11 | |
| St. Joseph's Academy (30-3) Class 4 District 4 | |
| TBD |
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| St. Dominic (24-10-2) Class 4 District 7 | |
| St. Teresa's Academy (25-4-2) Class 4 District 14 | |
| TBD |